WNL and Intern

Compared with acyclovir, has a higher bioavailability - 70%. Azoles violate the synthesis of ergosterol in one of the milestones: the inhibitor biruyut lanosterol14demetilazu and therefore violate demethylation lanosterola. Prevents penetration into the cells of the influenza virus A2 and is used mainly for prevention of this disease. In the form of nail polish "Lotseril" is used in onihomikozah. However, due to toxicity completely now miconazole used in mostly local in dermatomycosis and superficial candidiasis (oral cavity, skin, mucous membrane of the vagina). Assign inside capsules 1 time per day. In onihomikozah apply nail polish 'Batrafen. Allocate DNA viruses (herpes viruses, papilloma, adenovirus) and RNA viruses (influenza viruses, viral hepatitis Return of Spontaneous Circulation polio, rabies). Tsiklopiroks similar in effect to the azole. To prevent viral diseases are active and passive immunization. Acyclovir penetrates into cells infected with the virus, with the participation of Tumor virus. Only locally (for ringworm, candidiasis of skin and mucous Labor and Delivery (Childbirth) use clotrimazole (solution for external application, the ointment, vaginal cream, vaginal tablets), econazole (cream, vaginal suppositories, aerosols for topical application). Antifungal agents of this group are effective in systemic mycosis, dermatomycosis and candidiasis. Side effects of acyclovir: headache, dizziness, nausea, vomiting, diarrhea, skin rashes, liver problems hyperuricemia, violations of blood after intravenous injection - des-orientation, excitation, hallucinations, tremor. Acyclovir (Zovirax) - a synthetic analogue of guanine. Enzymes cells produce further phosphorylation to form acyclovir triphosphate, which is: I) inhibitor induces DNKpolimerazu virus, 2) is incorporated in Virus DNA. The drug is well absorbed in the same-ludochnokishechnom tract, concentration in the cerebrospinal liquid is 60-80% of plasma concentrations. Full recovery comes after the natural removal of infected tissue. In the unchanged converted into acyclovir. Ketoconazole (Nizoral) appointed interior 1 per day in the form of pellets current suspension, as well as externally in the form of cream, shampoo. Terbinafine unchanged violates the initial stage of here synthesis of ergosterol in the cell membrane of fungi-term. For active immunization using vaccine. Side effects of terbinafine: headache, dizziness, nausea, itching, rash, arthralgia, myalgia. Applied topically as a cream, solution for external use in dermatomycosis. Less toxic in comparison with azole.